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From74US$ /night
Check-in
14Mar2026Select date
Check-out
15Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

220 South Interstate Dr, Sikeston, Missouri, United States, 63801
-
Near the Sikeston Depot Museum & Gallery
Very good
7.2
7.2
/10
3.0
3.2
/5

Amenities

Days Inn And Suites By Wyndham Sikeston offers a comprehensive range of amenities, including a fitness center and a business center for work-related needs. Free parking is provided for vehicles of all sizes, including RVs and trucks. Guests can utilize barbecue grills for outdoor cooking and enjoy guest laundry facilities during their stay.

Rooms

The hotel features spacious suites equipped with separate living rooms, allowing guests to unwind comfortably. Each suite includes a desk, cable TV, microwave, mini-refrigerator, and ironing amenities. Pet-friendly rooms are also available for travelers accompanied by their furry friends.

Location

Situated in the Bootheel region of Missouri, the hotel is conveniently located halfway between St. Louis and Memphis. Guests can explore local attractions such as the Sikeston Rodeo Grounds, known for its concerts and events. The Sikeston Depot Museum offers insights into local history, making it a suitable day trip for visitors.

Business

For meetings and events, the hotel offers 5,500 square feet of event space, accommodating up to 100 banquet guests. Two meeting rooms are available to facilitate business conferences or special occasions. Group rates are provided to ensure affordability for larger gatherings.

Dining

Guests start their day with a complimentary light breakfast item along with their choice of coffee, tea, and juice. This breakfast option allows visitors to fuel up before exploring the area. While dining options are not plentiful on-site, numerous restaurants are located nearby.

Highlights

Location: halfway between St. Louis and Memphis

Rooms: separate living rooms and pet-friendly options

Amenities: 5,500 square feet of event space

Dining: free light breakfast item and beverages

“Days Inn And Suites By Wyndham Sikeston presents an interesting layout, formerly a retirement community, now offering spacious suite-style rooms. I noted some cleanliness issues during my exploration of the available information and read about inconsistent experiences. For travellers prioritizing space and a unique building conversion over modern polish, this could be a reasonable option.”
Hotel logo
James DavidEditor-in-Chief at Cheaphotels
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Select your room type

The hotel provides a selection of rooms—doubles, family rooms, and suites—with perks like free cancellation, breakfast options, and great value deals
One-Bedroom Deluxe King Suite Non-Smoking
2 persons
520 sq. feet 
1 King-size bed
Shower
Coffee machine
One-Bedroom King Suite Non-Smoking
2 persons
520 sq. feet 
Shower
Coffee machine
One-Bedroom Deluxe Queen Suite Non-Smoking
2 persons
520 sq. feet 
2 King Size Beds
Shower
Coffee machine
One-Bedroom Suite Two Queen Beds Non-Smoking
2 persons
520 sq. feet 
Shower
Coffee machine
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Amenities & services

Real traveler stories and honest reviews—no glossy ads, just authentic feedback to guide your booking
Facilities: Very good
7.1/10Review score

General

  • No smoking on site
  • Wi-Fi
  • 24-hour reception
  • Pets allowed
  • Luggage storage
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Meeting/ Banquet facilities
  • Fax/Photocopying

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Dressing area
  • Patio

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Parquet floor
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Days Inn And Suites By Wyndham Sikeston Location

220 South Interstate Dr, Sikeston, Missouri, United States, 63801
Map view
220 South Interstate Dr, Sikeston, Missouri, United States, 63801
Restaurants
McDonald's
1200 ft
2605 E Malone
Explore Sikeston
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Malco Sikeston Cinema and Grill
Malco Sikeston Cinema and Grill
10-minute drive
A modern cinema featuring the latest films with comfortable seating and an extensive menu.
Sikeston Depot Museum & Gallery
Sikeston Depot Museum & Gallery
15-minute drive
A historical museum showcasing local history and artifacts, perfect for culture enthusiasts.
Sikeston Sports Complex
10-minute drive
A comprehensive sports facility offering various fields and courts for local games and events.
Golfing at Boot Heel Golf Club
10-minute drive
An 18-hole golf course offering challenges for all skill levels, with rental services available.
Outdoor Fun at Sikeston Sports Complex
10-minute drive
Enjoy various outdoor sports activities, from baseball to walking trails, all in a scenic environment.
McDonald's
McDonald's
5-minute walk
A classic fast-food restaurant known for its burgers and fries, perfect for a quick meal.
Sikeston Diner
10-minute drive
A cozy spot offering traditional American diner food with generous portions and friendly service.
Malco
10-minute drive
A local favorite for catching the newest blockbusters, complete with arcade games and snack options.
Sikeston Sports Complex Events
10-minute drive
Hosts various sports events and competitions throughout the year, great for family outings.
Getting around town
City Centre
Sikeston8 min  ·  3.3 mi
Airports
Cape Girardeau Regional Airport (CGI)65 min  ·  26.9 mi
Barkley Regional Airport (PAH)132 min  ·  54.4 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in for free.
Breakfast
A continental breakfast is served and charges are applicable. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2012
Number of rooms:
60
Former name
Americas Best Value

Reviews and Ratings

What past guests shared about their stay
Review score
Based on 246 verified reviews
7.3/10
Very good
65%
Recommend
Breakfast
5.9/10
Cleanliness
7.8/10
Comfort
7.6/10
Facilities
7.1/10
Free Wi-Fi
7.4/10
Location
8.1/10
Paid Wi-Fi
5.9/10
Staff
8.1/10
Value for money
7.5/10
Pros
Clean rooms
Helpful staff
Comfortable beds
Nice lobby
Welcome feeling
Cons
Broken pullout
Tiny bathroom
Guest reviews
based on 228 reviews
7.2/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Days Inn And Suites By Wyndham Sikeston
What are the check-in and check-out times at Days Inn And Suites By Wyndham Sikeston?
Check-in is at 15:00 and check-out is at 11:00.
How far is Days Inn And Suites By Wyndham Sikeston from Cape Girardeau Regional Airport?
The hotel is 44 km from Cape Girardeau Regional Airport, which takes approximately 35 minutes to drive.
What room amenities are available at Days Inn And Suites By Wyndham Sikeston?
Rooms feature air conditioning, a flat-screen TV, a refrigerator, a coffee machine, free toiletries, and a desk.
What are the fitness options at Days Inn And Suites By Wyndham Sikeston?
There is a fitness center available for guests to use.
Is breakfast included at Days Inn And Suites By Wyndham Sikeston?
Guests can enjoy a continental breakfast at the hotel.
What parking options are available at Days Inn And Suites By Wyndham Sikeston?
The hotel offers complimentary on-site parking for guests.
Which attractions are close to Days Inn And Suites By Wyndham Sikeston?
Nearby attractions include Sikeston Depot Museum & Gallery (6 km) and Malco Sikeston Cinema and Grill (10 minutes' drive).
What are the cleaning services provided at Days Inn And Suites By Wyndham Sikeston?
The hotel offers laundry services for guests.
What local dining options are available near Days Inn And Suites By Wyndham Sikeston?
Nearby dining options include Jds Steakhouse and Saloon, Lamberts Cafe, and El Bracero, all within a short drive.

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Check-in
14Mar2026Select date
Check-out
15Mar2026Select date
Rooms and Guests2 Guests, 1 Room